The Science of Anabolic Steroid Abuse (Auchus)

Academic endocrinology lecture by Dr. Richard J. Auchus (UT Southwestern, Division of Endocrinology & Metabolism) on the science of anabolic-androgenic steroids (AAS). An external clinical/scientific reference — not Justin's protocol. ^[1]

Myths vs Reality

Common medical myths: AAS are used mostly by pro athletes, users die of cancer/liver failure/strokes, it's "not germane to my practice," and they have no place in good medicine. Reality: use is common in the general population (children to businessmen — an entire subculture), AAS are very addicting in specific users, clinicians will encounter users, and androgens play a prominent legitimate role in medicine (HIV, cancer, critical illness, the elderly). ^[1]

Anabolic vs Androgenic

• Anabolic: ability to aid assimilation of nutrients (nitrogen) into tissue.
• Androgenic: masculinizing properties.
• "Weak androgens" are precursors of strong (DHEA, androstenedione); strong = testosterone, dihydrotestosterone.
• The two properties have thus far been inseparable — presumed same mechanism of action. ^[1]